FBN1 and isolated ectopia lentis: Therefore, our present results would indicate that the correlation observed with ectopia lentis is supported by isoform FBN1_004. Furthermore, a significant association was found in patients between the expressions of FBN1_004 and FBN1_009. This suggests that variations in the expression of both these isoforms have an impact on the pathogenesis of ectopia lentis.