However, the levels of C/EBPβ protein were not very different among adenocarcinomas with mutant K-RAS (A549, H23, A427, NCI-H358), mutant EGFR (NCI-H1975, HCC827) and wild-type K-RAS and EGFR (NCI-H1703, NCI-H522, Calu-3) [40,41,42,43,44], even though A549 and H23 cells displayed relatively high levels of C/EBPβ (Figure 2A). Here, KRAS is linked to adenocarcinoma.