IL6 and cancer: In cancer cachexia, lipolysis is activated by various factors, including enhanced stimulation of β-adrenergic receptors; increased secretion of cytokines, such as TNF-α, IL-1, IL-6, and interferon-γ; and increased expression of lipid-mobilizing factors, such as zinc-α2 glycoprotein-1 (AZGP1) [37].