TNNI3 and atrial fibrillation: In a subanalysis of the Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction 48 (ENGAGE AF-TIMI 48) trial, a multimarker risk score including cardiac troponin I, N-terminal pro-B-type natriuretic peptide, and D-dimer levels was developed [16].