We focused on two cancer types, LUAD and ESCC from TCGA cbioportal (http://www.cbioportal.org/; Data S1), as TCGA and existing literature (Sawada et al., 2016; Seo et al., 2012) reported a significant reduction of Cdh23 expression in these two cancers for their respective patient cohort. Here, CDH23 is linked to esophageal squamous cell carcinoma.