Isolated mitochondria from PD patients were found to contain alpha‐synuclein.69 Alpha‐synuclein has been shown to have a strong affinity to mitochondria.67 This may be because alpha‐synuclein has an affinity to cardiolipin, which is found throughout the IMM.70 Due to this relationship between alpha‐synuclein and mitochondria, research has been directed into understanding the changes in mitochondria in PD, and other synucleinopathies. The gene discussed is SNCA; the disease is Parkinson disease.