COL11A1 and malignant colon neoplasm: In this study, we perform integrated analysis including differently expressed genes, gene ontology (GO) analysis, KEGG pathway analysis, survival analysis both to identify a panel of key candidate genes involved in colon cancer, and we found that SPP1, VIP, COL11A1, CA2, ADAM12, and INHBA could provide great significant prognostic value for colon cancer.