The upregulated genes are mainly enriched in C‐X‐C chemokine receptor(CXCR) binding, cytokine activity, chemokine activity, chemokine receptor binding, G‐protein coupled receptor binding, IL‐17 signaling pathway, rheumatoid arthritis, cytokine‐cytokine receptor interaction, chemokine signaling pathway, Toll‐like receptor signaling pathway. This evidence concerns the gene IL17A and rheumatoid arthritis.