The miscarriage risk decreased with simultaneous presence of the VEGFA -634 CG and VEGFA -2578CC genotype (OR 0.38, 95% CI 0.19–0.78, p=0.01) (Figure 1) and VEGFA -2578CC, VEGFA -634CG, TGFB1 936CC genotype (OR 0.45, 95% CI 0.21–0.96, p=0.057) (Figure 2). The gene discussed is TGFB1; the disease is spontaneous abortion.