The anti-tumorigenic properties of both ApoA1 and ApoA1 mimetics have been recently explored in different types of malignancies, including melanoma (Zamanian-Daryoush et al., 2013), colorectal (Gkouskou et al., 2016), and ovarian cancer (Su et al., 2010; Gao et al., 2011, 2012, Ganapathy et al., 2012). Here, APOA1 is linked to melanoma.