APOE and schizophrenia: In addition, the most significant pathways related to the selected proteins, namely altered acute inflammatory response [involving ANT3, APOA2, A2AP, FETUA, HPT, and ITIH4; gene ontology (GO) term GO:0002526, false discovery rate (FDR) = 1.6 × 10–7] and ultra-low density lipoprotein transport (APOA2, APOA4, APOC3 and APOE; GO:0034378, GO:0034371 and GO:0034370, FDR < 1.0 × 10−6) in schizophrenia, are consistent with previous reports36,38.