PDPN and cancer: Podoplanin has previously been reported to enhance the migration of cancer-associated MSC lines (Suchanski et al., 2017; Martin-Villar et al., 2010; Neri et al., 2015; Wicki et al., 2006; Petrie et al., 2012), and, where analysed, MSCs and ECs associated with with specialised lymphoid tissues (Navarro et al., 2011; Langan et al., 2018; Astarita et al., 2015).