Importantly, as soon as 30 min after ischemia onset, up to 60% of the ischemia-affected vessels displayed an endothelial edema (Fig. 4c), whereas 1 h after ischemia onset even 13% of the striatal vessels showed endothelial cells with cytoplasmic accumulations of FITC-albumin indicating an impaired cellular integrity (Fig. 4d). Here, ALB is linked to ischemia.