There was a significant correlation between the expression of TFF3 in breast carcinoma cells and response to chemotherapy (p = 0.0165) as 58% (58) of residual carcinomas express TFF3 and 66% (22) of cases with complete response did not express TFF3 in pre-neoadjuvant biopsies (Fig. 7a) (Additional file 1: Table S1). This evidence concerns the gene TFF3 and carcinoma.