In a previous study in which miR-200c was highly expressed while Nkx2.1 was knocked down, the active delivery of miR-200c increased by 16.7-fold [26], especially when delivered in a Nano vehicle, because miR-200c has been previously shown to enhance radio sensitivity with an antitumor activity drug association in lung cancer [27, 28]. The gene discussed is NKX2-1; the disease is lung cancer.