SYK and neuroblastoma: To further explore the effect of SYK on neuroblastoma cell viability, we transfected SH-SY5Y, SK-N-BE(2), and SK-N-AS cells with expression vectors encoding different FLAG-tagged SYK variants (SYK wt = SYK wild type, SYK B = short SYK splice variant B, SYK Y130E = constitutive active SYK, SYK K402R = kinase dead SYK, SYK RR42/195KK = SYK with inactive SH2 domains).