Surprisingly, FRTL5-Ras-PATZ1-injected mice developed tumors at least one month earlier than FRTL5-Ras-Ctrl controls, and tumor engraftment rate was 100% (6 out of 6) in mice injected with FRTL5-Ras-PATZ1 cells, against 60% (3 out of 5; one mouse died for unknown reasons and was excluded from the experiment) in mice injected with control cells (Figure 1a). This evidence concerns the gene PATZ1 and neoplasm.