Specifically for MLP it was striking to note that a) increased phosphorylation of MLP correlates with dilated cardiomyopathy (DCM) in patients, and b) MLP mutations associated with hypertrophic cardiomyopathy (HCM) result in decreased phosphorylation, while mutations associated with DCM development displayed markedly increased MLP phosphorylation [42]. The gene discussed is CSRP3; the disease is dilated cardiomyopathy.