Mice transplanted with CSF2RB− IL1RL1− KIT− cells had the longest time to leukemia development and the lowest penetrance with statistically significant differences in survival as compared to mice transplanted with CSF2RB−, IL1RL1−, KIT+/− cells at the 10,000 cell dose (Fig. 3B–D and Supplemental Table S1). Here, IL1RL1 is linked to leukemia.