Recently, a study has reported that epithelial‐mesenchymal transition (EMT) is associated with cancer cell invasion and metastasis.5 During EMT, markers of mesenchymal cell such as vimentin and N‐cadherin are upregulated, conversely, markers of epithelial cell such as β‐catenin and E‐cadherin are downregulated.6 Eventually, the cell polarity of epithelial tumor cells is lost,7 and the cells are loosely connected.8 At the same time, tumor cells are more susceptible to attack and metastasis. This evidence concerns the gene CDH2 and neoplasm.