Few recent studies have shown the crucial role of Nanog in tumorigenesis of lung adenocarcinoma,33 gastric adenocarcinoma,34 and colorectal cancer.35 In our analyses, the elevated expression of Nanog was significantly correlated with the Nr5a2 amplification (Figure 5A) and with elevated Nr5a2 expression in NSCLC patient samples of advanced stage (Figure 6). The gene discussed is NANOG; the disease is lung adenocarcinoma.