Over 10 years ago, results of a data set from a College of American Pathologists (CAP) Proficiency Testing Survey assessing over 1100 transfusion service practices for non‐alloimmunised SCD patients demonstrated that less than 30% of North American hospital transfusion service laboratories determined SCD patients' baseline RBC serologic phenotype beyond ABO and Rh(D) and issued RBC units that were matched for Rh (C/c, E/e) and Kell antigens (Osby & Shulman, 2005). Here, ABO is linked to Schnyder corneal dystrophy.