LRRK2 and Parkinson disease: An experiment in nematodes suggested that leucine rich repeat kinase (Lrrk) offers protection against rotenone induced DA cell loss, and that RGS2 (Regulator Of G Protein Signaling 2) modulates pathway activities between LRRK2 and the PD-associated genes, PINK1 and DJ-1 (Dusonchet et al., 2014).