We found that TRAIL-R2, but not TRAIL-R1, was upregulated on the surface of CIB1-depleted versus control MDA-436 TNBC cells, starting 2 days post-infection with both CIB1-1 and CIB1-2 shRNA sequences (Fig. 4a, b; Additional file 2: Figure S1F, G). The gene discussed is TNFRSF10B; the disease is infection.