AFP and ovarian cancer: In a recent case report of a giant panda (Ailuropoda melanoleuca) with ovarian cancer, histopathological studies revealed multiple lesions in the lungs, kidneys, perianal tissue and spleen at necropsy, that stained positive by immunohistochemistry for B7-H4, CA125, and HE4, as well as the presence of significantly high serum levels of the tumour antigen AFP [23].