2011; Yang et al. 2017). Previously, we found that RISK pathway activation stemming from liver RIPC reduced the severity of I/R‐induced ventricular arrhythmias in a rat model. We also observed increased phosphorylation of myocardial kinases ERK1/2 and further GSK‐3β at Ser9 but not Tyr216 in the rat model (Hu et al. 2016). Here, MAPK3 is linked to Ventricular arrhythmia.