MAP4 and neoplasm: With low calpain-1 expression associating with stage 1 tumour (Zhang et al. 2018), in the current study, low Syk-c and MAP4 expression also related to organ-confined status (Syk-c: χ2 = 9.975, df = 1, P = 0.002; and MAP4: χ2 = 15.402, df = 1, P = 0.000087) (Tables 2, 3).