SYK and cancer: Expression has been found negatively associated with cell proliferation and anchorage-independent growth; moreover, negative associations have also been detected between Syk and cell migration, lymphovascular invasion, microvessel density and/or metastasis formation in cancers (Ogane et al. 2009; Fei et al. 2013; Nakashima et al. 2006; Coopman and Mueller 2006; Peng et al. 2013; Chuanliang et al. 2016).