MAP4 and neoplasm: In chemotherapy-naïve cases (n = 448), low Syk-c, low Syk-n and low MAP4 also showed significant association with organ-confined status of tumour (Syk-c: χ2 = 10.551, df = 1, P = 0.001; Syk-n: χ2 = 5.041, df = 1, P = 0.025; MAP4: χ2 = 14.322, df = 1, P = 0.000154).