Current findings are in contrast to those from a previous study conducted in ovarian cancer cells where Syk expression/activity levels positively associated with cell resistance to paclitaxel; moreover, in the same study, pharmacological and genomic Syk inhibitors had a synergistic effect with paclitaxel both in vitro and in vivo especially in cells that were resistant to paclitaxel (Yu et al. 2015). Here, SYK is linked to ovarian cancer.