Conversely, when we overexpressed NQO1 in TE-11R cells via lentivirus infection (Fig. 5e, f), NQO1 overexpression resulted in a decrease of 8-OHdG-indicated oxidative damage after THC treatment (Fig. 5g) and was associated with resistance to THC treatment (Fig. 5h). The gene discussed is NQO1; the disease is lentivirus infection.