A few approaches to insulin administration have been proposed, but major criticisms include inappropriate insulin dose leading to either persistent hyperglycaemia or significant (9.5%) risk of hypoglycaemia [15], reduced imaging quality due to diffuse skeletal muscle and myocardial uptake due to glucose transporter type 4 (GLUT4)-mediated uptake in these tissues [16]. Here, INS is linked to Hyperglycemia.