Baseline characteristics between the PP and MD subgroups of Cohort 2 were also similar (Table 2), with the exception of existing insulin therapy for diabetes (37.9% [PP] vs 69.7% [MD], P < 0.0017) and weight (87 kg ± 20.8 [PP] vs 97 ± 23.9 kg [MD], P < 0.035) indicating that knowledge of patient’s existing insulin therapy and increased weight may have prompted the nuclear medicine physician to adjust the PIC recommended dosage. The gene discussed is INS; the disease is diabetes mellitus.