Excluding the ribosomal protein pathways, the top 5 pathways (based on the observed count of input proteins) are: broad axonopathy spectrum: mRNA Processing, Protein processing in the endoplasmic reticulum, Viral carcinogenesis, Spliceosome, and Apoptosis; CMT2-dominant: HIF-1 signaling pathway, Aminoacyl-tRNA biosynthesis, Biosynthesis of amino acids, Carbon metabolism, and Glycolysis and Gluconeogenesis; and HSP-dominant: Epstein-Barr virus infection, Herpes simplex infection, and Antigen processing and presentation. This evidence concerns the gene HSP90B2P and herpes simplex infectious disease.