To assess the effect of miR-500a-5p on tumour growth in vivo, LoVo/m-NC, LoVo/miR-500a-5p, LoVo/Vector, LoVo/HDAC2, and LoVo/miR-500a-5p/HDAC2 cells were implanted subcutaneously into nude mice, and the growth of the resultant primary tumours was monitored (Fig. 4a). Here, HDAC2 is linked to neoplasm.