FMR1 and esophageal squamous cell carcinoma: And this result was confirmed in the validation set (Guangzhou: 107, HR = 1.784; 95%CI = 1.06–3.004; P = 0.0163) and the pooled set (HR = 1.761; 95%CI = 1.259–2.462; P = 0.0006), the high serum FMR1-AS1 group showed a lower OS of female ESCC patients (Fig. 5h).