Moreover, the silencing of MyD88 could also hinder the NFκB-c-Myc signaling cascades and phenotype transition through FMR1-AS1 exosome incubation in the ESCC cells (Fig. 6d-f, Additional file 11: Figure S6b and Additional file 4). This evidence concerns the gene MYD88 and esophageal squamous cell carcinoma.