PRMT1 and non-small cell lung carcinoma: Furthermore, cellular apoptosis induced by doxorubicin along with the PRMT5 knockdown or PRMT1 overexpression could be inhibited by the exogenous replenishment of CFLARL, suggesting that PRMT5 and PRMT1 affect apoptosis by regulating the protein level of CFLARL in NSCLC cells.