SPAG5 and breast cancer: Then, we examined MYCBP expression in 183 breast cancer patients using IHC and found that MYCBP protein expression is positively correlated with SPAG5 expression in breast cancer (R = 0.218, p < 0.001, Additional file 7: Fig. S3b), as well as in TNBC (R = 0.321, p < 0.001, Fig. 5d, e).