When compared to the low FN1 expression group, the high FN1 expression group had significantly larger tumor size (P = 0.002), more advanced T stage (P = 0.039) and N stage (P = 0.009), and worse AJCC stage (54.0% vs 28.7% with stage III, P = 0.003) (Table 2). The gene discussed is FN1; the disease is neoplasm.