The variation of tumor markers including carcino-embryonic antigen (CEA, normal range, 0–0.5 ng/mL) and carbohydrate antigen 72–4 (CA72–4, normal range, 0–6.9 U/mL) are showed in Fig. 6 for each visit from the initial treatment to the present. The gene discussed is CEACAM5; the disease is neoplasm.