Here either H2B-RFP B16F10 mouse melanoma cells were injected into a GFP mouse, H2B-RFP/Cre B16F10 cells were injected into a R26R-stop-YFP transgenic mouse, or fl-dsRED-fl-GFP B16F10 cells were injected into a Cre mouse [29]. Here, H2BC21 is linked to melanoma.