Chronic low-grade systemic inflammation as measured by slightly to moderately elevated high sensitivity CRP (hsCRP) has gained clinical attention based on epidemiological studies indicating its role as an independent predictor of type 2 diabetes mellitus (T2DM) [4, 5], cardiovascular morbidity, and cardiovascular as well as all-cause mortality [2, 6–9]. The gene discussed is CRP; the disease is type 2 diabetes mellitus.