CRP and obesity due to melanocortin 4 receptor deficiency: There were no significant differences in traditional CVD risk factors between patients and controls; however, our data indicate the possible influence of comorbidities (e.g., obesity, hypertension, hyperlipidemia) and unhealthy behaviors (e.g., sedentarism, smoking) [40], given that the psoriatic patients who had subclinical atherosclerosis were older, with significantly higher BMI, waist circumference, insulin resistance, and serum CRP values, and were more frequently hypertensive in comparison to those who did not.