It was also recently reported that Nrf2 plays a role in cellular metabolism.25 Cancer cells reprogram the cellular metabolism to acquire more necessary nutrients in a nutrient‐deprived environment, for example, a low‐oxygen environment, and proliferate more efficiently26 Therefore, the inhibition of the Keap1/Nrf2 pathway was also predicted to be important for inhibiting cancer metabolism, which may lead to tumor progression inhibition. The gene discussed is NFE2L2; the disease is cancer.