CDK4 and type 2 diabetes mellitus: For example in the cell cycle, miRNAs we find to be associated with T2DM progression directly regulate the expression of cyclins (CCNG1), cyclins‐dependent kinases (CDK10, CDK4, CDK6), DNA helicases (MCM10, MCM3), and transcription factors (E2F3, E2F5, FOXN3).