Further, the results of the concept elicitation activities described herein indicate that HR+/HER2- advanced breast cancer affects individuals’ ability to function physically, such as walking, ability to do housework, and ability to cook, as well as impacting other areas of their lives (due to physical limitations or other attributes of their condition), such as family, social life, work, and emotional well-being. This evidence concerns the gene ERBB2 and breast cancer.