Consistent with the DIAPH1 expression patterns observed in glioma, colorectal and breast cancers, and oral squamous cell carcinoma [6, 16–18], IHC and western blotting of paired LSCC and ANT tissues showed that DIAH1 was overexpressed in LSCC. The gene discussed is DIAPH1; the disease is oral cavity squamous cell carcinoma.