DIAPH1 and neoplasm: Second, we analyzed clinical and mRNA expression data of 500 patients with HNSCC, from TCGA, and found that in class G3, high DIAPH1 expression was significantly associated with poor OS (p = 0.002, Figure 1(b)) and that the expression of DIAPH1 was higher in tumor tissues than in adjacent normal tissues (Figure 1(c)).