Moreover, because different types of HNSCCs, such as LSCC and hypopharyngeal squamous cell carcinoma, have distinctively different biologic behaviours, we analysed GSE65858 dataset based on different primary sites and found the trend that high DIAPH1 expression was associated with poor OS in LSCC (Figure 1(d)). Here, DIAPH1 is linked to hypopharynx squamous cell carcinoma.