CD8A and neoplasm: Considering that the proliferation of polyclonal CD44hi CD8+ T cells occurs in both the dLN and tumor in a similar B16F10 subcutaneous tumor model (7), the tumorminor/dLNmajor clones may proliferate greatly in the dLN but not in the tumor, whereas the tumormajor/dLNminor clones that predominate the T cell repertoire in the tumor may proliferate weakly in the dLN but greatly in the tumor.