Importantly, although JQ1 was shown to reduce STAT5 function in hematologic cancers and dendritic cells, there is no information regarding this or other BETi effects on (1) the IL-2 signaling pathway via STAT5 in Tregs as well as (2) IL-2 production which is required for Treg survival and their maintenance of suppressive function (21, 22). The gene discussed is IL2; the disease is hematopoietic and lymphoid cell neoplasm.