TWIST1 and neoplasm: EMT is a process that increases the invasiveness of tumor characterized by the loss of epithelial-cadherin (E-cadherin) and the enhanced expression of transcription factor snail family transcriptional repressor 1 (SNAI1) gene (also referred to as Snail), transcription factor snail family transcriptional repressor 2 (SNAI2) gene (also referred to as Slug), forkhead box C1 (FOXC1), twist-related protein 1(TWIST1), neural cadherin (N-cadherin), and Vimentin.