In addition, the functions of DDX5 in tumorigenesis, apoptosis, and cancer development such as breast cancer (Guturi et al., 2014), prostate cancer (Clark et al., 2008), colorectal cancer (Dai et al., 2018), and esophageal cancer (Ma et al., 2017) have been established, but the role of DDX5 in OS remains unclear. The gene discussed is DDX5; the disease is esophageal cancer.