CD274 and posterior cortical atrophy: The pooled HR for BCR-FS showed that PD-L1 expression was associated with poor BCR-FS in PCa with statistical significance and a higher level of PD-L1 expression increased the risk of death by 78 % with fixed effects (HR = 1.78; 95 % CI 1.39 to 2.27; p < 0.00001) (Figure 4A).