NAPA, FLOT2, TPM1, NDRG4, ARPC5, DLD, MBL2, PSMA4, VDAC2 were only detected in the malignant PNs group, while Q59FP5 (protein ID), FBN1, CSF1, CSPG3, KIF5B-ALK, IGKV2D-28, LAMB1, CD81, VASN, CFHR4, IL7R, HLA-B were only detected in the benign PNs group. The gene discussed is NDRG4; the disease is paraneoplastic neurologic syndrome.