Apart from that, based on the study led by Anfossi et al. who analyzed plasma samples from IBC, non-IBC and healthy individuals, it was identified that the over-expression of miR-19a in serum was closely associated with a preferable clinical outcome in patients suffered from metastatic HER2+ IBC, which may represent a credible molecular bio-marker for prognosis of IBC patients [37, 50]. Here, ERBB2 is linked to inflammatory breast carcinoma.