Although the difference in gene expression between Msx1 wt and Msx1-deficient tumor cells was rather negligible (one of the significance criteria, i.e. q-value < 0.05, was never reached), a set of differentially expressed genes (significance criterion: |logFC| ≥ 1 and p-value ≤ 0.05) was identified (the gene set is given in Supplementary Table S4) and analyzed using the online tool Enrichr22,23. The gene discussed is MSX1; the disease is neoplasm.